A Clearinghouse for Information about Blood Clots (DVT/)PE) and Clotting Disorders (thrombophilia) provided as a public service by the University of North Carolina Blood Research Center

Author: Clot Connect

  • Acute Proximal DVT – Offering Patients Enrollment into ATTRACT Trial

    If you as a health care professional are involved in the management of patients with acute (proximal) DVT, please consider giving the patient (who has leg symptoms ≤ 14 days) an opportunity to be enrolled in the national ATTRACT trial (information on the trial is here). This NIH-funded, multi-center trial investigates whether catheter-directed thrombectomy (±…

  • PFO (Patent Foramen Ovale)

    A discussion of PFO and paradoxical embolism, written for patients, is available on the Clot Connect Patient blog- connect here.  The health care professional can refer his/her patient to the information on PFO in that blog . The blog also contains images suitable for patients to understand the etiology of  paradoxical embolism:

  • HIT (Heparin-Induced Thrombocytopenia)

    A detailed discussion of Heparin-Induced Thrombocytopenia (HIT) written for patients is available on the Clot Connect Patient blog- connect here. We hope that the health care professional will consider this document to be suitable as an information handout to his/her patients with HIT. The discussion also contains 2 resources for use by the health care provider:

  • DVT and PE: Symptoms and Risk Factors

    A detailed discussion of the symptoms of and risk factors for DVT and PE, written for patients, is available on the Clot Connect Patient blog- connect here. We hope that the health care professional will find this document suitable to be printed out as a handout for patients and their family members whom they want…

  • Cerebral Venous Thrombosis

    Stephan Moll, MD writes… 2011 Consensus Statement A superb, comprehensive and thoughtful expert summary was published for health care professionals in February 2011 [ref 1]. It gives a wealth of solid recommendations on diagnosis and treatment.

  • Progestin-only Contraceptives and Thrombosis

    Background It is well known that combination contraceptives (containing estrogens AND progestins) increase the risk for venous thromboembolism (VTE). Relatively few data, however, have been published on progestin-only contraceptives, so that until recently it was not clear whether they increase the risk for venous thromboembolism (VTE) or not.

  • Family Member Testing For Thrombophilia

    Background If a thrombophilia (clotting disorder) has been identified in a patient with blood clots (venous thromboembolism = VTE), the question arises whether other family members should be tested for the same thrombophilia. My Clinical Approach My approach in clinical practice to thrombophilia testing in family members is summarized in table 1: Family Member Testing. If the patient

  • Dental Work on Warfarin

    A number of dental procedures can be done safely withouthaving to discontinue warfarin. A clinically helpful table is can be found here: Dental procedures and Warfarin (from ref 1).