A Clearinghouse for Information about Blood Clots (DVT/)PE) and Clotting Disorders (thrombophilia) provided as a public service by the University of North Carolina Blood Research Center

Category: Women and blood clots

  • Heavier Menstrual Bleeding on Xarelto?

    Stephan Moll, MD writes… Interesting and noteworthy observations published in the last 2 weeks:  Heavy menstrual bleeding appears to occur more commonly with Xarelto® than with warfarin [ref 1] and may be also more common with Xarelto® than with Eliquis® [ref 2].

  • Contraceptive Use While on Anticoagulants is Safe

    Stephan Moll, MD writes… Interesting and clinically relevant publication this week [ref 1].  It is well known that estrogens and certain progestin preparations increase the risk for venous thromboembolism (VTE).  A woman on an anticoagulant may have heavy menstrual bleeds and hormonal therapy – such as estrogen-progestin contraceptives – may be considered to decrease the bleeding.…

  • Thrombophilia – Information Handout for Patients

    Stephan Moll, MD writes… An information article on various aspects of thrombophilia, written for patients and family members, was published today – available here – as a Vascular Disease Patient Information Page in the journal Vascular Medicine.  It addresses (a) in which patient with venous thromboembolism to consider thrombophilia  testing, (b) what tests might be appropriate to do, (c) how the test results…

  • How Long is the Post-Partum Period in Respect to Thrombosis Risk?

    Stephan Moll, MD writes… A recent NEJM study (ref 1) examined whether the risk for thrombosis in women persists beyond the first 6 weeks after delivery.  It found that an increased risk persists for at least 3 months after delivery, although the absolute risk was low after the first 6 weeks.  This is of clinical…

  • Skyla – A New IUD, Suitable for Women at Risk for DVT and PE

    Dr. Stephan Moll writes… Skyla® is a new IUD (intrauterine device) contraceptive, approved in February 2013 by the FDA.  Skyla® is like a small version of the Mirena® IUD.  It has the following features:

  • Yasmin, Yaz and Other Drospirenone Contraceptives: Risk for VTE

    It has long been known that estrogen-containing birth control preparations (pill, patch, ring) increase the risk for DVT and PE (venous thromboembolism = VTE).  This risk is partially due to the estrogen.  However, part of the risk is also due to the type of progestin in these preparations.

  • Yasmin, Yaz, Angeliq and Risk for Blood Clots

    Birth control pills, patches and rings typically contain an estrogen and a progestin component.  It has long been known that estrogen-containing birth control preparations (pill, patch, ring) increase the risk for blood clots (DVT, PE).  This risk is partially due to the estrogen.  However, part of the risk for clots is also due to the…

  • Pregnancy and Blood Clots: Prevention, Diagnosis, Treatment

    A new guideline about the prevention, diagnosis, and treatment of DVT and PE associated with pregnancy was published today by ACOG (American College of Obstetricians and Gynecologists) in its respected series of Practice Bulletins.  The bulletin also takes detailed reference to prevention of blood clots in pregnant women with thrombophilia.