A Clearinghouse for Information about Blood Clots (DVT/)PE) and Clotting Disorders (thrombophilia) provided as a public service by the University of North Carolina Blood Research Center

Category: warfarin / coumadin

  • Warfarin-Induced Skin Necrosis

    How common is it? Warfarin-induced skin necrosis is a rare complication of warfarin (coumadin®, Jantoven®) therapy. It occurs in approximately 1 of 10,000 patients treated with warfarin. What is it? Patients with warfarin-induced skin necrosis develop very painful skin areas, most commonly in the breasts,

  • Warfarin-Induced Skin Necrosis

    How common is it? Warfarin-induced skin necrosis is a rare complication of warfarin (coumadin®, Jantoven®) therapy. It occurs in approximately 1 of 10,000 patients treated with warfarin. What is it? “Necrosis” means “dead tissue”. Patients with warfarin-induced skin necrosis develop very painful skin areas, most commonly in the breasts, next commonly in buttocks, thighs and…

  • Purple Toe Syndrome

    Warfarin can, in rare instances, cause violaceous painful discoloration of the toes and the sides of the feet, referred to as the “purple toe syndrome” 1 – see photograph below. Occasionally, the hands can also be involved and a net-like skin rash on abdomen and legs (= livedo reticularis) can occur. This typically happens within the…

  • Purple Toe Syndrome

    Warfarin can, in rare instances, cause violaceous painful discoloration of the toes and the sides of the feet, referred to as the “purple toe syndrome” 1 – see photograph below. Occasionally, the hands can also be involved and a net-like skin rash on abdomen and legs (= livedo reticularis) can occur. This typically happens within the…

  • Hair Loss on Warfarin

    How common is it? Hair loss is a known side effect of warfarin, but has hardly been studied [ref 1]. Solid data on how frequently it occurs, on its time-course, and on treatments are  not available. Mild hair loss appears to be common, severe hair loss uncommon, complete hair loss has not been reported.

  • Hair Loss on Warfarin

    How common is it? Hair loss is a known side effect of warfarin (Coumadin®, Jantoven®), but has hardly been studied [ref 1]. Solid data on how frequently it occurs, on its time-course, and on treatments are  not available. Mild hair loss appears to be common, severe hair loss uncommon, complete hair loss has not been…

  • Dental Work on Warfarin

    A number of dental procedures can be done safely withouthaving to discontinue warfarin. A clinically helpful table is can be found here: Dental procedures and Warfarin (from ref 1).

  • INRs that Fluctuate – Solutions

    Background and summary The cause  of fluctuating INRs in patients on warfarin is often not clear.  The following causes should be considered. Solutions how to deal with fluctuating INRs are listed further below.