A Clearinghouse for Information about Blood Clots (DVT/)PE) and Clotting Disorders (thrombophilia) provided as a public service by the University of North Carolina Blood Research Center

Category: Uncategorized

  • Athletes and DVT + PE

    Background Many people think of DVT and PE as a problem occurring in elderly people, but not in young and apparently healthy individuals. While it is certainly true that they occur more commonly in the elderly and in non-athletic overweight individuals, they can, nevertheless, happen in young, normal weight, and athletic people.

  • Testosterone and Thrombosis

    Testosterone Replacement Therapy Replacement therapy with low doses of testosterone does not adversely affect blood coagulation status [ref 1] and does not appear to increase the risk of venous or arterial thrombosis. Thrombosis is not listed as a potential side effect in the commly used drug compendium (Micromedex). Furthermore, the 2006 “Clinical Practice Guideline” from the…

  • HHT

    What is HHT? HHT (Hereditary Hemorrhagic Teleangiectasia), called Osler-Weber-Rendu syndrome,  is an inherited disorder in which small blood vessels develop abnormally [ref 1].  It is estimated that 30,000 to 60,000 people (1 out 5,000 to 10,000) in the United States are affected. Individuals with HHT develop telengiectasias in the skin (usually in the fingers and hands) and…

  • Acute Proximal DVT – Offering Patients Enrollment into ATTRACT Trial

    If you as a health care professional are involved in the management of patients with acute (proximal) DVT, please consider giving the patient (who has leg symptoms ≤ 14 days) an opportunity to be enrolled in the national ATTRACT trial (information on the trial is here). This NIH-funded, multi-center trial investigates whether catheter-directed thrombectomy (±…

  • PFO (Patent Foramen Ovale)

    A discussion of PFO and paradoxical embolism, written for patients, is available on the Clot Connect Patient blog- connect here.  The health care professional can refer his/her patient to the information on PFO in that blog . The blog also contains images suitable for patients to understand the etiology of  paradoxical embolism:

  • HIT (Heparin-Induced Thrombocytopenia)

    A detailed discussion of Heparin-Induced Thrombocytopenia (HIT) written for patients is available on the Clot Connect Patient blog- connect here. We hope that the health care professional will consider this document to be suitable as an information handout to his/her patients with HIT. The discussion also contains 2 resources for use by the health care provider:

  • DVT and PE: Symptoms and Risk Factors

    A detailed discussion of the symptoms of and risk factors for DVT and PE, written for patients, is available on the Clot Connect Patient blog- connect here. We hope that the health care professional will find this document suitable to be printed out as a handout for patients and their family members whom they want…

  • Cerebral Venous Thrombosis

    Stephan Moll, MD writes… 2011 Consensus Statement A superb, comprehensive and thoughtful expert summary was published for health care professionals in February 2011 [ref 1]. It gives a wealth of solid recommendations on diagnosis and treatment.