A Clearinghouse for Information about Blood Clots (DVT/)PE) and Clotting Disorders (thrombophilia) provided as a public service by the University of North Carolina Blood Research Center

Category: Uncategorized

  • New Comprehensive Clinical Guidance on VTE Treatment

    Stephan Moll, MD writes… A new consensus guidance on management of venous thromboembolism (VTE) – link here – was published today, Jan 18th, 2016, in the Journal of Thrombosis and Thrombolysis.  The publication contains 13 chapters on various aspects of VTE

  • ACCP Guideline for DVT and PE Treatment: New Edition, 2016

    The ACCP Chest Guidelines have been the main guide over the last more than 2 decades for evidence-based recommendations on best management of anticoagulants for various indications, including DVT and PE.  The 10th edition of the chapter on DVT and PE management was published in Jan 2016 [ref 1]. Unfortunately, the guideline is not available for non-subscribers.

  • Scuba Diving While on an Anticoagulant

    Stephan Moll, MD writes… Can patients on anticoagulants safely scuba dive?  In general: “Yes”.  Many people who take anticoagulants are able to safely dive.  However, there are a few things to consider:

  • MTHFR and Homocysteine: Information Handout for Patients

    Stephan Moll, MD writes… A plain language summary for patients and interested public about homocysteine and the MTHFR mutations and their relevance in respect to thrombosis was  published today in the journal Circulation (link here). Reference:  Moll S, Varga EA.  Homocysteine and MTHFR Mutations. Circulation. 2015;132:e6-e.

  • Warfarin Interruption for Surgery: Bridging with LMWH Often Not Needed

    Stephan Moll, MD writes:  Interesting and relevant publication today in the New England Journal of Medicine (NEJM)

  • Reversal Agent for Pradaxa: Important NEJM Publication Today

    Stephan Moll, MD writes… A publication in the New England Journal of Medicine today reports on the use of the Pradaxa® (Dabigatran) antidote Idarucizumab in patients on Pradaxa® who present with major bleeding or require urgent surgery [ref 1]. 

  • Thrombophilia – Information Handout for Patients

    Stephan Moll, MD writes… An information article on various aspects of thrombophilia, written for patients and family members, was published today – available here – as a Vascular Disease Patient Information Page in the journal Vascular Medicine.  It addresses (a) in which patient with venous thromboembolism to consider thrombophilia  testing, (b) what tests might be appropriate to do, (c) how the test results…

  • ASH 2014 Highlights: Thrombosis and Anticoagulation

    Stephan Moll, MD writes… The annual American Society of Hematology (ASH) meeting took place in Dec 2014 in San Francisco.  A summary of the clinically relevant thrombosis and anticoagulation presentation and abstracts is presented here (Top 10 ASH Highlights).   Disclosure: I have been a consultant to Portola, Daiichi, Janssen, and Boehringer-Ingelheim.  Last updated: Jan…