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FDA Approval for Apixaban (Eliquis) for A. Fib.
Stephan Moll, MD writes… Today (Dec 28th, 2012) the FDA approved apixaban for the prevention of stroke and systemic arterial thromboembolism in patients with atrial fibrillation, based on the ARISTOTLE study [ref 1]. The FDA press release is here.
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Does Aspirin Prevent Recurrent DVT and PE? – ASPIRE Trial
Stephan Moll, MD writes… Well, it is not clear whether it does. A clinically relevant study (ASPIRE study) was published this week (Nov 22nd,2012) in the N Engl J Med [ref 1]. In patients who had a previous unprovoked (= idiopathic) DVT or PE and who had completed standard length (often considered to be 3-6 months)…
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Xarelto (Rivaroxaban): FDA Approved for DVT and PE Treatment
Stephan Moll, MD writes… Today is a very exciting day for patients and health care professionals: the oral anticoagulant Xarelto® (rivaroxaban) was FDA approved today (Nov 2nd, 2012) for the use in patients with DVT and PE – for the acute treatment of DVT and PE, as well as for the secondary long-term prevention of…
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TTP with I.V. Use of Pain Medication OpanaER
Stephan Moll, MD writes… The CDC published an alert on Oct 26th, 2012, that they are investigating 12 cases of TTP (thrombotic thrombocytopenic purpura) in drug users who injected intravenously the opioid pain medication Opana ER® (oxymorphone extended-release), a medication made as a tablet and meant for oral use. The tablet was pulverized by the drug…
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ACCP 2012 Guidelines: A Great, New, User-Friendly Summary
Stephan Moll, MD writes… The more than 20 chapters and 801 pages of the respected 2012 ACCP Antithrombotic Therapy Guidelines – beautifully evidence-based, but always very cumbersome to read for the clinician looking for quick management guidance -, have now been summarized by the ACCP into a visually appealing, uncluttered, clinician-user-friendly document, referred to as…
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Behind the headlines: Does eating lunch at your desk increase blood clot risk?
Beth Waldron, Program Director of Clot Connect, writes… The claim: “Eating lunch at your desk could increase your risk of DVT”—was the dramatic headline from UK’s Marie Claire magazine which caught my attention. (1) The online story went on to say that “Almost 75 per cent of office staff aged 21-30 who work 10-hour days…
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Frequently asked patient questions: When will my clot and pain go away?
Following the diagnosis of deep vein thrombosis or pulmonary embolism, a patient may ask “When will my clot and pain go away?” An answer, written for patients, can be found on Clot Connect‘s patient education blog, here. This is the first in a series of posts designed to answer many of the most commonly asked…
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Ischemic Colitis and Thrombophilia
Stephan Moll, MD writes… Ischemic colitis is an uncommon and typically benign disorder. For mostly unclear reasons, multiple small vessels in the colonic wall have decreased perfusion or become occluded, resulting in patchy, superficially ulcerated areas. Typically, no surgical intervention is needed and the patient recovers spontaneously within 1-2 weeks. Often patients have only one episode. Few…
