A Clearinghouse for Information about Blood Clots (DVT/)PE) and Clotting Disorders (thrombophilia) provided as a public service by the University of North Carolina Blood Research Center

Category: Uncategorized

  • Argatroban Nomogram

    Stephan Moll, MD writes…. The treatment of heparin induced thrombocytopenia may require the use of argatroban. Here is the argatroban nomogram  used at our institution, the University of North Carolina (UNC) at Chapel Hill. Disclosure: I have no financial disclosures relevant to this post. Last updated: June 25th, 2013

  • Klippel-Trenaunay Syndrome, DVT and PE

    Stephan Moll, MD writes…  Klippel-Trenaunay Syndrome (KTS) is a rare congenital disorder of capillary, venous and lymphatic malformations and a localized disturbed growth of bone and/or soft tissue (see photographs)[ref 1].  Patients with KTS are at significantly increased risk for DVT, PE and superficial thrombophlebitis.  KTS affects only one side of the body, typically the leg or the…

  • Aspirin Prevents Recurrent DVT and PE – WARFASA Study

    Stephan Moll, MD writes… A clinically very relevant study (WARFASA) published today (May 24, 2012) in the New England Journal of Medicine [ref 1] shows that aspirin, 100 mg per day, reduces the risk of recurrent venous thromboembolism (VTE) in patients with unprovoked (= idiopathic) VTE, who have completed 6 to 18 months of anticoagulant therapy, without…

  • Which Patient With DVT or PE to Refer to a Specialist?

    Stephan Moll, MD writes…  Not every patient with DVT or PE needs the same type of physician.  The best combination for a patient to have may be (a) a primary care provider, (b)  a health care professional in a formal Warfarin Clinic and (c) a physician with special expertise in thrombosis, and a primary care provider,  for a…

  • Recovery After a DVT or PE

    Stephan Moll, MD writes…  A discussion for patients of questions commonly asked after a DVT are discussed here, in Clot Connect’s patient blog, such as: How quickly can I expect improvement? How active can I be after a DVT or PE? When can I go back to doing sports? When is it safe to fly again…

  • Compression stockings after DVT

    In the patient with deep vein thrombosis-DVT who has leg pain and swelling, their leg may feel better with use of compression stockings.   Compression stockings may also prevent post-thrombotic syndrome-PTS. Detailed information about compression stockings, written for patients, is available in this post. A handout on compression stockings which you can print to provide patients…

  • Rivaroxaban (Xarelto) and PE

    Stephan Moll, MD writes… Good news: The large phase 3 clinical trial comparing 3-12 months treatment of Rivaroxaban (Xarelto) with warfarin in patients with newly diagnosed pulmonary embolism was published on 3-26-2012 in the New England Journal of Medicine [reference 1], showing that Rivaroxaban was (a) noninferior to warfarin in its efficacy, (b) caused the…

  • INR Self-Testing

    Stephan Moll, MD writes… A detailed, practical discussion on INR self-testing for patients is available here, addressing: Reasons to do INR self-testing Which patients are suitable What INR home monitoring devices are available Whether the devices give reliable INR results Whether insurance companies pay for them