A Clearinghouse for Information about Blood Clots (DVT/)PE) and Clotting Disorders (thrombophilia) provided as a public service by the University of North Carolina Blood Research Center

Category: Whom to test

  • Thrombophilia – Information Handout for Patients

    Stephan Moll, MD writes… An information article on various aspects of thrombophilia, written for patients and family members, was published today – available here – as a Vascular Disease Patient Information Page in the journal Vascular Medicine.  It addresses (a) in which patient with venous thromboembolism to consider thrombophilia  testing, (b) what tests might be appropriate to do, (c) how the test results…

  • Three Things We Shouldn’t Do

    Stephan Moll, MD writes…  The American Society of Hematology (ASH) has identified 3 things that physicians dealing with DVT, PE and anticoagulation should avoid – published today [ref 1].

  • Pregnancy Loss and Thrombophilia

    How common is pregnancy loss? What are the causes? Pregnancy loss  in the general population is common. Most losses occur in the first trimester. As many as 5 % of women have 2 or more early losses; 1-2 % have 3 or more early losses [ref 1]. Well established risk factors for pregnancy loss are:…

  • Family Member Testing For Thrombophilia

    Background If a thrombophilia (clotting disorder) has been identified in a patient with blood clots (venous thromboembolism = VTE), the question arises whether other family members should be tested for the same thrombophilia. My Clinical Approach My approach in clinical practice to thrombophilia testing in family members is summarized in table 1: Family Member Testing. If the patient