A Clearinghouse for Information about Blood Clots (DVT/)PE) and Clotting Disorders (thrombophilia) provided as a public service by the University of North Carolina Blood Research Center

List of posts


  • Stephan Moll, MD writes (last updated: Sept 9th, 2020)… Background:  Hospitalized patients with COVID-19 are at increased risk for thrombosis – DVT, PE, and may be pulmonary micro-vascular thrombosis that possibly contributes to respiratory failure; arterial events appear to occur less commonly. Scientific/clinical data on prevalence of thrombosis, best prevention, and optimal therapy are limited.

    Read more

  • A. Is it ok for me to get the COVID-19 vaccine? Yes, it is ok to take for pretty much all individuals, no matter whether they have a clotting disorder (=thrombophilia), have had a blood clot (DVT or PE), or are on a blood thinner. Reasons NOT to get the vaccine have to do with

    Read more

  • Beth Waldron writes (Last updated May 7, 2020) There is help available for many people who can’t afford their anticoagulant (blood thinning) medication. Many pharmaceutical companies provide free or discounted medicines through prescription assistance programs, also called PAPs. Each program is administered by the pharmaceutical company and has its own qualifying criteria. We are unaware

    Read more

  • Dr. Stephan Moll and Beth Waldron write (last updated April 28, 2020): The company making Coumadin® (warfarin sodium) tablets, Bristol-Myers Squibb (BMS), announced that it will discontinue the sale and distribution of Coumadin® (see the FDA filing here). A memo on the BMS website says: “all strengths of Coumadin® (warfarin sodium) tablets will be discontinued

    Read more

  • Beth Waldron, MA writes….For patients on life-saving therapies like blood thinners (anticoagulants) having several weeks supply of medication on hand during the coronavirus outbreak is important not only to reduce the need to be out in public, but to ensure you have everything you need already at home if you do get sick. However, getting

    Read more

  • Dr. Stephan Moll writes (last updated: March 27th, 2020)… Background and Questions: Infection with COVID-19 can lead to a coagulopathy. Are any of the coagulation markers helpful to predict good or bad outcome? Which coagulation tests should be obtained in hospitalized patients? Should the coagulopathy be treated and, if yes, how? Two separate documents were

    Read more

  • Dr. Stephan Moll writes (last updated: March 25th, 2020)… Question: Can a person who needs to be on a blood thinner and who has had gastric banding or gastric bypass surgery for weight loss be on Eliquis®, Xarelto®, Pradaxa®, or Savaysa®? Answer: Warfarin is currently the preferred choice, because the absorption of the direct oral anticoagulants

    Read more

  • Stephan Moll, MD writes… On June 23, 2017, the FDA approved a 5th new oral anticoagulant for clinical use, Bevyxxa® (= Betrixaban). It is approved to prevent DVT and PE in patients who are significantly immobile during and after hospitalization for an acute medical illness. Full prescribing information: here.  FDA details: here. In the APEX study

    Read more

  • Stephan Moll, MD and Damon Houghton, MD write … In patients with antiphospholipid syndrome (APS) who require anticoagulation for the treatment of DVT or PE, warfarin or a low molecular weight heparin have traditionally been used. A question that comes up is whether one of the new oral anticoagulants (DOACs) can be effectively and safely

    Read more

  • Stephan Moll, MD writes… Can the patient with acute DVT or PE safely fly, or should he/she wait for a few weeks before embarking on airline travel?  It appears safe to fly early: There is no evidence that flying early after the diagnosis of VTE leads to an increased risk of recurrent VTE or embolization

    Read more