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Stephan Moll, MD writes (last updated: Sept 9th, 2020)… Background: Hospitalized patients with COVID-19 are at increased risk for thrombosis – DVT, PE, and may be pulmonary micro-vascular thrombosis that possibly contributes to respiratory failure; arterial events appear to occur less commonly. Scientific/clinical data on prevalence of thrombosis, best prevention, and optimal therapy are limited.
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Eliquis (Apixaban) is one of the 4 promising new oral anticoagulants that (a) do not require routine monitoring of its anticoagulant effect and (b) work independently of the vitamin K pathway.
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Eliquis (Apixaban) is one of the 4 promising new oral “blood thinners” that (a) do not require monitoring of its “blood thinning” (anticoagulant) effect, i.e. do not require INR monitoring, and (b) do not interfere with vitamin K in the diet, i.e. patients can eat what they want.
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What topics need to be discussed with the patient who wants to start Pradaxa (Dabigatran)? A structured, bulleted checklist may be helpful in your discussion with the patient, to make sure all relevant points are addressed. A suggested list is here.
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What topics do you need to discuss with your physican or anticoagulation clinic pharmacist or nurse when you are considering starting Pradaxa (Dabigatran)? A structured, bulleted checklist may be helpful for the discussion, to make sure that all relevant points are addressed. A suggested list is here.
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Inherited protein C deficiency is considered a stronger thrombophilia. It increases the risk for venous and arterial thromboembolism, and possibly for early and late pregnancy loss and other adverse pregnancy outcomes (preeclampsia, IUGR, placental abruption). There are 2 major causes for low protein C values:
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What is Protein C? Protein C is a protein in our blood stream, which prevents blood from clotting too much. It’s a sort of police protein that keeps our clotting in check. If protein C levels are low, a person will have a tendency to clot more easily. Elevated levels of protein C, on the
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How common is pregnancy loss? What are the causes? Pregnancy loss in the general population is common. Most losses occur in the first trimester. As many as 5 % of women have 2 or more early losses; 1-2 % have 3 or more early losses [ref 1]. Well established risk factors for pregnancy loss are:
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How common is pregnancy loss? What are the causes? Pregnancy loss (= miscarriage) in the general population is common. Most losses occur in the first trimester. As many as 5 % of women have 2 or more early losses; 1-2 % have 3 or more early losses [ref 1]. Well established risk factors for pregnancy
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If you are on warfarin (Coumadin®, Jantoven®) you need to be followed in a structured way to optimize your warfarin therapy and minimize the risk for bleeding and clotting. The “thinness” of your blood needs to be determined on a regular basis with a test called INR (International Normalized Ratio; also referred to as PT, protime,
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Patients on warfarin need to be followed in a systematic way to optimize safety and efficacy of therapy [ref 1]. While smaller-volume physician practices may well have appropriate criteria in place, structured anticoagulation clinics often have the expertise and resources for optimal anticoagulation management. The location of a number of anticoagulation clinics in the U.S.
