A Clearinghouse for Information about Blood Clots (DVT/)PE) and Clotting Disorders (thrombophilia) provided as a public service by the University of North Carolina Blood Research Center

Tag: anticoagulant

  • Safe Pain Medications on Warfarin

    Certain pain medications increase the risk of bleeding in patients on warfarin (coumadin®, Jantoven).  Two mechanism can be at play: (1) non-steroidal pain medications (NSAIDs = non-steroidal anti-inflammatory drugs) may lead to gastritis which can lead to bleeding into the stomach, made worse by being on “blood thinners”, and (2) pain medications taken on a…

  • Pradaxa Approval – Great News!

    The new oral anticoagulant Pradaxa® (Dabigatran) was approved by the FDA on October 20th, 2010 [ref 1,2]. As of Feb 3rd, 2012, Pradaxa® is only FDA approved for use in patients with atrial fibrillation. It is not approved yet for patients with DVT and PE.

  • Dental Work on Warfarin

    A common question from patients and dentists is whether warfarin needs to be interrupted at times of dental procedures, such as cleaning or pulling of teeth or root canals. Medical publications and recommendations from the dental community outlining best management of patients on warfarin exist (ref 1-6). However, even though evidence suggests that stopping warfarin for…

  • Pradaxa approval – Great news!

    Summary The new oral “blood thinner” Pradaxa® (=Dabigatran) was approved by the FDA on October 20th, 2010 (ref 1 and 2). This is huge news! This is the first oral blood thinner alternative to warfarin (=Coumadin®, Jantoven®). At this point, Pradaxa® is only FDA approved for use in patients with irregular heart beat (= atrial…