A Clearinghouse for Information about Blood Clots (DVT/)PE) and Clotting Disorders (thrombophilia) provided as a public service by the University of North Carolina Blood Research Center

Tag: Deep vein thrombosis

  • HHT

    What is HHT? HHT (Hereditary Hemorrhagic Teleangiectasia), called Osler-Weber-Rendu syndrome,  is an inherited disorder in which small blood vessels develop abnormally [ref 1].  It is estimated that 30,000 to 60,000 people (1 out 5,000 to 10,000) in the United States are affected. Individuals with HHT develop telengiectasias in the skin (usually in the fingers and hands) and…

  • HHT

    What is HHT? HHT (Hereditary Hemorrhagic Teleangiectasia) is an inherited disorder in which small blood vessels develop abnormally [ref 1].  It is also called Osler-Weber-Rendu syndrome. It is estimated that 30,000 to 60,000 people (1 out every 5,000 to 10,000) in the United States have it. Individuals with HHT develop small abnormal blood vessels (teleangiectasias)…

  • Acute Proximal DVT – Offering Patients Enrollment into ATTRACT Trial

    If you as a health care professional are involved in the management of patients with acute (proximal) DVT, please consider giving the patient (who has leg symptoms ≤ 14 days) an opportunity to be enrolled in the national ATTRACT trial (information on the trial is here). This NIH-funded, multi-center trial investigates whether catheter-directed thrombectomy (±…

  • New DVT – Optimizing Treatment – ATTRACT Trial

    If you or somebody you know has been diagnosed in the last 14 days with a new DVT of the leg (thigh or pelvic veins), I would encourage you to consider participation in the ATTRACT trial – a solid, clinically useful study (NIH funded) that investigates how to minimize the long-term complications after a blood clot –…

  • PFO = Patent Foramen Ovale

    Anatomy Some people have a “hole in the heart”, called a “patent foramen ovale” (PFO). This is a connection between the right and the left chamber (atrium) of the heart. We are all born with it – the unborn needs this connection for proper blood circulation. In most people the hole closes in the first…

  • HIT = Heparin-induced Thrombocytopenia

    What Is HIT? Heparin-induced thrombocytopenia (HIT) is a serious side effect that may occur when you are being treated with heparin. It may lead to low blood platelet counts and to life-threatening blood clots.

  • Symptoms of DVT and PE

    DVT (Deep Vein Thrombosis) A DVT is a blood clot that most commonly occurs in the leg, typically only one leg (image 1). However, occasionally it occurs in both legs at the same time (=bilateral DVT). Sometimes, a DVT is in the pelvic veins or the big abdominal vein (=inferior vena cava). And some DVTs…

  • Arm and Leg Veins – Anatomy and Terminology

    Confusion as to which veins of arms and legs are superficial and which are deep can lead to an incorrect diagnosis. As treatment of clots in superficial veins (= superficial thrombophlebitis) is different to that of clots in deep veins (DVT = deep vein thrombosis), the distinction between superficial and deep veins is important.