A Clearinghouse for Information about Blood Clots (DVT/)PE) and Clotting Disorders (thrombophilia) provided as a public service by the University of North Carolina Blood Research Center

Tag: protein C

  • Protein C Deficiency

    Inherited protein C deficiency is considered a stronger thrombophilia. It increases the risk for venous and arterial thromboembolism, and possibly for early and late pregnancy loss and other adverse pregnancy outcomes (preeclampsia, IUGR, placental abruption).  There are 2 major causes for low protein C values:

  • Thrombophilia Testing – Who Should be Tested?

    Background and Consensus Guidelines No general consensus exists as to which patients with blood clots and which family members should be tested for thrombophilias.  At least five guidelines or consensus statements exist (ref 1-5).  They vary markedly in their recommendations as to who should be tested and who not,