A Clearinghouse for Information about Blood Clots (DVT/)PE) and Clotting Disorders (thrombophilia) provided as a public service by the University of North Carolina Blood Research Center

List of posts


  • Stephan Moll, MD writes (last updated: Sept 9th, 2020)… Background:  Hospitalized patients with COVID-19 are at increased risk for thrombosis – DVT, PE, and may be pulmonary micro-vascular thrombosis that possibly contributes to respiratory failure; arterial events appear to occur less commonly. Scientific/clinical data on prevalence of thrombosis, best prevention, and optimal therapy are limited.

    Read more

  • The annual meeting of the American Society of Hematology (ASH) took place in San Diego from Dec 10-13, 2011.  Abstracts on thrombosis and anticoagulation that I found  interesting and clinically relevant  are summarized and put into a clinical perspective in this summary document.  Only one abstract was, in my assessment, clinical-practice-changing – abstract #543: “Aspirin after

    Read more

  • To some degree it does, but it is by far not as effective as warfarin or other anticoagulants. However, a very noteworthy study was presented today

    Read more

  • Beth Waldron, Program Director of Clot Connect writes… Research has shown that effective communication between a patient and their doctor can improve the patient’s health outcome.[i]  If you have been diagnosed with deep vein thrombosis (DVT) or pulmonary embolism (PE), you understandably have many questions.  In an ideal world, a health care provider would have

    Read more

  • Today the FDA approved Xarelto (Rivaroxaban) for irregular heart beat (= atrial fibrillation = a. fib).  The approved dose is 20 mg once daily.  The link to the FDA press release is here.  The Xarelto prescribing information can be found here. Xarelto for Blood Clots in the Veins (DVT and PE)

    Read more

  • Today the FDA approved Xarelto (Rivaroxaban) for atrial fibrillation.  The approved dose is 20 mg once daily. The link to the FDA press release is here.  The Xarelto prescribing information can be found here. Xarelto for Venous Thromboembolism Xarelto is NOT approved at this point for treatment of DVT or PE

    Read more

  • A new guideline was published this week about venous thromboembolism (VTE) prophylaxis in hospitalized medical sick patients and in stroke patients [link here; ref 1]. The key points of this guideline,

    Read more

  • A patient may ask: “I am on warfarin.  Is it o.k. for me to drink alcohol?  Does alcohol intake increase the INR?”   Does drinking alcohol change the INR in the patient on warfarin?

    Read more

  • A patient may ask: “I am on warfarin (Coumadin®, Jantoven®).  Is it o.k. for me to drink alcohol?  Does alcohol intake increase the INR?” Does drinking alcohol change the INR in the patient on warfarin?

    Read more

  • Phytoestrogens (plant estrogen preparations) are sometimes used in the attempt to improve perimenopausal symptoms, such as hot flashes, night sweats, vaginal dryness or mood swings.  They are plant-derived estrogens, chemically similar (even though distincly different) to human and animal estrogens

    Read more

  • Phytoestrogens (plant estrogen preparations) are sometimes used in the attempt to improve perimenopausal symptoms, such as hot flashes, night sweats, vaginal dryness or mood swings.  They are plant-derived estrogens, chemically similar (even though distincly different) to human and animal estrogens

    Read more